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UniProtKB/Swiss-Prot Q14690: Variant p.Leu1216Phe

Protein RRP5 homolog
Gene: PDCD11
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Variant information Variant position: help 1216
Type of variant: help LB/B
Residue change: help From Leucine (L) to Phenylalanine (F) at position 1216 (L1216F, p.Leu1216Phe).
Physico-chemical properties: help Change from medium size and hydrophobic (L) to large size and aromatic (F)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 1216
Protein sequence length: help 1871
Location on the sequence: help KFRVGQALRATVVGPDSSKT L LCLSLTGPHKLEEGEVAMGR
Residue conservation: help 
Human                         KFRVGQALRATVVGP-DSSKTLLCLSLTGPHK-------LEEGEVAMGR

Mouse                         KFQVGQAIEATVVDP-DVPRAFLCLSLIGPYR-------LE

Bovine                        KFQIGQALKATVVGPAESSKAFLCLSLIGPHK-------LK

Drosophila                    -----------------ISNKKLDIAHISPS----------

Baker's yeast                 VFPLGSALQVKVA---SIDREHGFVNAIGKSHVDINMSTIK

Fission yeast                 HFFLGKAIKCYVV---NAE-DSITLSAIGPLQ---GFENLT
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 2 – 1871 Protein RRP5 homolog
Domain 1149 – 1222 S1 motif 10



Literature citations
Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.
Nagase T.; Seki N.; Ishikawa K.; Tanaka A.; Nomura N.;
DNA Res. 3:17-24(1996)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANT PHE-1216; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1442; VARIANT PHE-1216;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.