Variant position: 169 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 485 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human SAETLREILQDKELSKEQLV AFLENVLKTSGKLRENLLHGA
Mouse SPESIREILQDREPSKEQLV AFLENLLKTSGKLRATLLHGA
Bovine SAETLREILQDKELSKEQLV AFLENLLNTSGKLRENLLHGA
Xenopus laevis CTQHL------KELPRDQLV KWLEDPAGKLEFLRHELLYGA
Drosophila VKDH---------PRKAKCP TLLKHQSTCSGPTSNSL----
Protein sequences conserved in prokaryotic aminoacyl-tRNA synthetases are important for the activity of the processivity factor of human mitochondrial DNA polymerase.
Carrodeguas J.A.; Bogenhagen D.F.;
Nucleic Acids Res. 28:1237-1244(2000)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; VARIANT THR-169;
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS THR-169 AND ALA-416;
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