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UniProtKB/Swiss-Prot Q7Z402: Variant p.Thr635Ile

Transmembrane channel-like protein 7
Gene: TMC7
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Variant information Variant position: help 635
Type of variant: help LB/B
Residue change: help From Threonine (T) to Isoleucine (I) at position 635 (T635I, p.Thr635Ile).
Physico-chemical properties: help Change from medium size and polar (T) to medium size and hydrophobic (I)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 635
Protein sequence length: help 723
Location on the sequence: help IIPLTISISRIPSSKACGPF T NFNTTWEVIPKTVSTFPSSL
Residue conservation: help 
Human                         IIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPSSL

Mouse                         IIPLTISMARIPSSKACGPFTNFNTTWEVIPQTVSTFPSSL

Chicken                       FVPLGVSIALISSSKACGPFRNFNTSWAIVPYTILEFPIGL
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 723 Transmembrane channel-like protein 7
Topological domain 623 – 665 Extracellular
Glycosylation 638 – 638 N-linked (GlcNAc...) asparagine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.