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UniProtKB/Swiss-Prot Q2VPK5: Variant p.Met253Val

Cytoplasmic tRNA 2-thiolation protein 2
Gene: CTU2
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Variant information Variant position: help 253
Type of variant: help LB/B
Residue change: help From Methionine (M) to Valine (V) at position 253 (M253V, p.Met253Val).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 253
Protein sequence length: help 515
Location on the sequence: help RTLTAKEELLQTLRTHLILH M ARAHGYSKVMTGDSCTRLAI
Residue conservation: help 
Human                         RTLTAKEELLQTLRTHLILHMARAHGYSKVMTGDSCTRLAI

Mouse                         KTLTAKEELLQTLRTHLIVHIARVHGYCKVMTGETCTRLAI

Rat                           KTLTAKEELLQTLRTHLTVHVARSHGYRKVMTGESCTRLAI

Bovine                        KTLTAKEELLQTLRTHLILHVARNHGYSKVMTGDSCTRLAI

Xenopus tropicalis            KTLTAKHQLLHTLRSHLILHIARTCGYSKVMSGESCTRLSV

Zebrafish                     KTLSAKQEMLQTLRQHLILHVARENSYSKVMMGESCSRLAV

Caenorhabditis elegans        SVPTYRKELERVLKEKCLQKIACSMGILKCMVPDHADDLGR

Drosophila                    RSLTARQDYLQQQRKNLICSVAQCLQCTHVFESNISVDLAT

Slime mold                    SSETSKEDLLLYYRNQLLIQVAHKLNCKKVILGTSSNRLAV

Baker's yeast                 LNNSSRSDLISIIKTQLIKHFAYENGYNAIMWGHSMTKLSE

Fission yeast                 SSLASRQDLLYRIRDKLLVSYARKANCDTIVFGDSGTTIAA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 2 – 515 Cytoplasmic tRNA 2-thiolation protein 2



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2); NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 42-515 (ISOFORM 3); VARIANTS VAL-253 AND ARG-416;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.