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UniProtKB/Swiss-Prot O95382: Variant p.Ser969Asn

Mitogen-activated protein kinase kinase kinase 6
Gene: MAP3K6
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Variant information Variant position: help 969
Type of variant: help LB/B
Residue change: help From Serine (S) to Asparagine (N) at position 969 (S969N, p.Ser969Asn).
Physico-chemical properties: help Change from small size and polar (S) to medium size and polar (N)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 969
Protein sequence length: help 1288
Location on the sequence: help QAPSQHPPSPPKRCLSYGGT S QLRVPEEPAAEEPASPEESS
Residue conservation: help 
Human                         QAPSQHPPSPPKRCLSYGGTSQLRVPEEPAAEEPASPEESS

Mouse                         QAPSQHPPSPPKRCLSYGDTSQLRVPEEPAAEEPASPEESS
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1288 Mitogen-activated protein kinase kinase kinase 6
Region 899 – 997 Disordered
Modified residue 964 – 964 Phosphoserine
Modified residue 984 – 984 Phosphoserine



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2); NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 435-1288 (ISOFORMS 1/3); VARIANTS ILE-455 AND ASN-969;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.