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UniProtKB/Swiss-Prot Q99856: Variant p.Gly556Ser

AT-rich interactive domain-containing protein 3A
Gene: ARID3A
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Variant information Variant position: help 556
Type of variant: help LB/B
Residue change: help From Glycine (G) to Serine (S) at position 556 (G556S, p.Gly556Ser).
Physico-chemical properties: help Change from glycine (G) to small size and polar (S)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 556
Protein sequence length: help 593
Location on the sequence: help AQPPAPTPTSAPNKGGGGGG G SSSNAGGRGGNTGTSGGQAG
Residue conservation: help 
Human                         AQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGT--SGGQAG

Mouse                         AQPPPPTAPSAPGKGGVSSIGTNTTTGSRTGASGSTVSGGQ

Xenopus laevis                AQPPT------------SASGTSKGSSNRTGSIGGGSSNSQ

Xenopus tropicalis            AQPPT------------SASGTSKGSSNRTGSIGGGSSTSQ

Zebrafish                     ARKPA--------IGFMPSSQRVHHQHSSQGKSNSPGLSSH
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 593 AT-rich interactive domain-containing protein 3A
Region 537 – 557 Important for cytoplasmic localization
Region 539 – 593 Disordered



Literature citations
A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer.
Suzuki M.; Okuyama S.; Okamoto S.; Shirasuna K.; Nakajima T.; Hachiya T.; Nojima H.; Sekiya S.; Oda K.;
Oncogene 17:853-865(1998)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; INTERACTION WITH E2F1; VARIANT SER-556; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS HIS-36; GLU-320 AND SER-556;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.