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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P35367: Variant p.Gly270Glu

Histamine H1 receptor
Gene: HRH1
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Variant information Variant position: help 270
Type of variant: help LB/B
Residue change: help From Glycine (G) to Glutamate (E) at position 270 (G270E, p.Gly270Glu).
Physico-chemical properties: help Change from glycine (G) to medium size and acidic (E)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 270
Protein sequence length: help 487
Location on the sequence: help KPGKESPWEVLKRKPKDAGG G SVLKSPSQTPKEMKSPVVFS
Residue conservation: help 
Human                         KPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFS

Gorilla                       KPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFS

Chimpanzee                    KPGKESPWEVLKRKPKDAGGGSVLKSPSQTXKEMKSPVVFS

Mouse                         KPGKESPWGVQKRPSRDPTGGLDQKSTSEDPK-VTSPTVFS

Rat                           KPGRESPWGVLKRPSRDPSVGLDQKSTSEDPK-MTSPTVFS

Bovine                        KPGKESPWEVLKRKPKDTGGGPVLKPPSQEPKEVTSPGVFS
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 487 Histamine H1 receptor
Topological domain 212 – 416 Cytoplasmic
Region 238 – 291 Disordered
Modified residue 279 – 279 Phosphothreonine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.