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UniProtKB/Swiss-Prot Q9BYC5: Variant p.Thr267Lys

Alpha-(1,6)-fucosyltransferase
Gene: FUT8
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Variant information Variant position: help 267
Type of variant: help LB/B
Residue change: help From Threonine (T) to Lysine (K) at position 267 (T267K, p.Thr267Lys).
Physico-chemical properties: help Change from medium size and polar (T) to large size and basic (K)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 267
Protein sequence length: help 575
Location on the sequence: help NWRYATGGWETVFRPVSETC T DRSGISTGHWSGEVKDKNVQ
Residue conservation: help 
Human                         N--WRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQ

                              N--WRYATGGWETVFRPVNETCTDRSGTSTGHWSGEVKDKN

Chimpanzee                    N--WRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKN

Mouse                         N--WRYATGGWETVFRPVSETCTDRSGLSTGHWSGEVNDKN

Rat                           N--WRYATGGWETVFRPVSETCTDRSGLSTGHWSGEVNDKN

Pig                           N--WRYATGGWETVFRPVSETCTDRSGSSTGHWSGEVKDKN

Bovine                        N--WRYATGGWETVFRPVSETCTDRSGVYTGHWSGEIKDKN

Xenopus tropicalis            S--WRYATGGWETVFKPVSETCTDRSGSSTGHWSGEANDKN

Caenorhabditis elegans        GSSWKYSSHGWTSVFKKLSKCSFDEAVGNTEAKP-FAEPSP

Drosophila                    G--WRYHKGGWEEVFQPVSNSCHDAGTANTYNWPGK---PN
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 575 Alpha-(1,6)-fucosyltransferase
Topological domain 31 – 575 Lumenal
Domain 206 – 493 GT23
Modified residue 278 – 278 Phosphoserine
Alternative sequence 15 – 420 Missing. In isoform 4.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.