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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot O95180: Variant p.Glu1974Gly

Voltage-dependent T-type calcium channel subunit alpha-1H
Gene: CACNA1H
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Variant information Variant position: help 1974
Type of variant: help LB/B
Residue change: help From Glutamate (E) to Glycine (G) at position 1974 (E1974G, p.Glu1974Gly).
Physico-chemical properties: help Change from medium size and acidic (E) to glycine (G)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 1974
Protein sequence length: help 2353
Location on the sequence: help ETYGAGTPLGSVASVHSPPA E SCASLQIPLAVSSPARSGEP
Residue conservation: help 
Human                         ETYGAGTPLGSVASVHSPPAESCASLQIPLAVSSPARSGEP

Mouse                         ETY-----TGPVTSAHSPSLEPRTSFQVPSAASSPARVSDP

Rat                           ETY-----TGPVTSAHSPPLEPRASFQVPSAASSPARVSDP
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 2353 Voltage-dependent T-type calcium channel subunit alpha-1H
Topological domain 1864 – 2353 Cytoplasmic



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.