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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q02643: Variant p.Met422Thr

Growth hormone-releasing hormone receptor
Gene: GHRHR
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Variant information Variant position: help 422
Type of variant: help LB/B
Residue change: help From Methionine (M) to Threonine (T) at position 422 (M422T, p.Met422Thr).
Physico-chemical properties: help Change from medium size and hydrophobic (M) to medium size and polar (T)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 422
Protein sequence length: help 423
Location on the sequence: help WRTRAKWTTPSRSAAKVLTS M C
Residue conservation: help 
Human                         WRTRAKWTTPSRSAAKVLTSMC

Mouse                         RRTCTEWTTPPRSRLKVLTSEC

Rat                           RRTCTEWTTPPRSRVKVLTSEC

Pig                           WRTHAKWAKPSRSRAKVLTTVC
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 23 – 423 Growth hormone-releasing hormone receptor
Topological domain 379 – 423 Cytoplasmic



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.