Variant position: 381 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 662 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GVDIPEDENEKMFFLIDKVN AFNQDITALMQGEETVGEEDI
Rhesus macaque GVDIPEDENEKMFFLIDKIN AFNQDITALIQGEETVGEDDS
Mouse GADIPEDDRTRMSFLVNKIS AFNRNIMNLIQAQETVSEGDS
Rat GADIPEDDSKRLSFLMNKIN VFNKDILSLVQAQENISWEES
Pig GSDIPEDESGKMFFLIDKID AFNSDITALIQGEELVVEYEC
Bovine GKDIPEEESEKMFCLIEKID TFNKEIISTIEGEEFVEQYDS
Sheep GKDIPEEESEKMFSLIEKID TFNKEIISTIEGEEHVGQYDS
Horse GTDIPEDETEKTFFLIVKIT TFNQNITSFVQGEELVGPNDT
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 662 Interferon-induced GTP-binding protein Mx1
2 – 662 Interferon-induced GTP-binding protein Mx1, N-terminally processed
366 – 533 Middle domain
367 – 632 Stalk
367 – 390
No reference for the current variant in UniProtKB/Swiss-Prot.
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