Variant position: 440 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 564 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VDAILGLAHHGNGQLRASLK EPEGPRSPAVFGAIISYFEQF
Mouse VNTILDLVHHANRQLRAVSK EASGPRSPTVFGAIISYVEQF
Bovine VDAVMDLVHHGNRQLKAASE EPRGPRSPAVLGAVVASVEHF
Xenopus laevis VDAVLDLIHHGNRQLKAVSK ESSSPRSPIVYGAMVSYIEQF
Xenopus tropicalis VDAVMDLIHHGNRQLKAVSK ESNSPRSSVVYGAMISYIEQF
Slime mold IKRLELLMKQTNESMNSIDT D--------LLFNVQDYVESI
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.