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UniProtKB/Swiss-Prot Q8IUR6: Variant p.Thr483Ala

CREB3 regulatory factor
Gene: CREBRF
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Variant information Variant position: help 483
Type of variant: help LB/B
Residue change: help From Threonine (T) to Alanine (A) at position 483 (T483A, p.Thr483Ala).
Physico-chemical properties: help Change from medium size and polar (T) to small size and hydrophobic (A)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 483
Protein sequence length: help 639
Location on the sequence: help NMYQKNGLHHGKYAVKKSRR T DVEDLTPNPKKLLQIGNELR
Residue conservation: help 
Human                         NMYQKNGLHHGKYAVKKSRRTDVEDLTPNPKKLLQIGNELR

Mouse                         NMYQKNGLHHGKYAVKKSRRTDVEDLTPNPKKLLQIGNELR

Drosophila                    PTCSVRGIKVYKHS-GKARKGDGNDLTPNARKLHNIGKELD
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 639 CREB3 regulatory factor
Alternative sequence 418 – 639 Missing. In isoform 2.
Alternative sequence 472 – 472 H -> HGK. In isoform 3.



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1); VARIANT ALA-483;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.