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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q68CJ6: Variant p.Arg23Pro

Nuclear GTPase SLIP-GC
Gene: NUGGC
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Variant information Variant position: help 23
Type of variant: help LB/B
Residue change: help From Arginine (R) to Proline (P) at position 23 (R23P, p.Arg23Pro).
Physico-chemical properties: help Change from large size and basic (R) to medium size and hydrophobic (P)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 23
Protein sequence length: help 796
Location on the sequence: help ETKDVFGQEPHPVEDDLYKE R TRKRRKSDRDQRFRAFPSME
Residue conservation: help
Human                         ETKDVFGQEPHPVEDDLYKERTRKRRKSDRDQRFRAFPSME

Mouse                         EMEALVGVVPHSADCDLFKEPVRKRRRLHRDRQFQAFPSAE

Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 796 Nuclear GTPase SLIP-GC
Region 1 – 35 Disordered



Literature citations
Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas.
Yamada S.; Ohira M.; Horie H.; Ando K.; Takayasu H.; Suzuki Y.; Sugano S.; Hirata T.; Goto T.; Matsunaga T.; Hiyama E.; Hayashi Y.; Ando H.; Suita S.; Kaneko M.; Sasaki F.; Hashizume K.; Ohnuma N.; Nakagawara A.;
Oncogene 23:5901-5911(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS PRO-23; ARG-328 AND ASN-474;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.