Variant position: 1600 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1782 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human AHVIKADSQDAGQETEKEGE EPQASAQDETPITSAKEESES
Mouse VPVMQADSQGAQQMLDKDES DLQVSPQDGTLSAVAQE----
Rat VPAMQADSQGAQQMLDKNE- ----SCQDETPSAAAQR----
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
2 – 1782 A-kinase anchor protein 12
1587 – 1587 Phosphoserine
Preparation of a set of expression-ready clones of mammalian long cDNAs encoding large proteins by the ORF trap cloning method.
Nakajima D.; Saito K.; Yamakawa H.; Kikuno R.F.; Nakayama M.; Ohara R.; Okazaki N.; Koga H.; Nagase T.; Ohara O.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1); VARIANTS GLU-117; GLN-216 AND ASP-1600;
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