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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q5T5U3: Variant p.Ala1727Thr

Rho GTPase-activating protein 21
Gene: ARHGAP21
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Variant information Variant position: help 1727
Type of variant: help LB/B
Residue change: help From Alanine (A) to Threonine (T) at position 1727 (A1727T, p.Ala1727Thr).
Physico-chemical properties: help Change from small size and hydrophobic (A) to medium size and polar (T)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 1727
Protein sequence length: help 1958
Location on the sequence: help KSARFKSDSGSLGDAKNEKE A PSLTKVFDVMKKGKSTGSLL
Residue conservation: help 
Human                         KSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLL

Mouse                         KSARFKSDSGSPGDTRTEKETPALAKMFDVMKKGKSTGSLL

Xenopus tropicalis            KSIRQKTDSECSAESKNEE---TLSDAQEAVKKGRSLS--I
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1958 Rho GTPase-activating protein 21
Region 1592 – 1861 Interaction with CTNNA1
Modified residue 1742 – 1742 Phosphoserine
Alternative sequence 1176 – 1958 Missing. In isoform 3.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.