Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q99759: Variant p.Ala435Gly

Mitogen-activated protein kinase kinase kinase 3
Gene: MAP3K3
Feedback?
Variant information Variant position: help 435
Type of variant: help LB/B
Residue change: help From Alanine (A) to Glycine (G) at position 435 (A435G, p.Ala435Gly).
Physico-chemical properties: help Change from small size and hydrophobic (A) to glycine (G)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 435
Protein sequence length: help 626
Location on the sequence: help LLKNLQHERIVQYYGCLRDR A EKTLTIFMEYMPGGSVKDQL
Residue conservation: help 
Human                         LLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQL

Mouse                         LLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQL
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 626 Mitogen-activated protein kinase kinase kinase 3
Domain 362 – 622 Protein kinase



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.