Variant position: 368 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 387 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human NQENDALHKKQLLNLWISDT MSSTEPPSKHAVTTSKMDII
Mouse GKESDAHRSKQLLNLQSSS- --------------------
Bovine NQENDAYHKKQLLNLHISNT VSYSEPPSKTAVSSPRMDIT
Xenopus laevis DVQIQELAQERLQSLHKET- ---PRTVKRNFQTSPRHKHH
Xenopus tropicalis DMEIRELAQERLQSLQKET- ---SRTVKRNLKNSPQRTHH
Zebrafish TIDTEAQRSQKILELRREI- --PSSSIPSWGLPQPT----
Drosophila EKQFLADEDQVKEKLRQRV- ----------GVVGPKIT--
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 387 GTP-binding protein 10
117 – 387 Missing. In isoform 3.
Isolation of full-length cDNA clones from human fetal brain cDNA library.
Mao Y.; Xie Y.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2); VARIANT ILE-368;
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