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UniProtKB/Swiss-Prot Q96KR1: Variant p.Ile520Thr

Zinc finger RNA-binding protein
Gene: ZFR
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Variant information Variant position: help 520
Type of variant: help LB/B
Residue change: help From Isoleucine (I) to Threonine (T) at position 520 (I520T, p.Ile520Thr).
Physico-chemical properties: help Change from medium size and hydrophobic (I) to medium size and polar (T)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 520
Protein sequence length: help 1074
Location on the sequence: help PKINFVGGNKLQSTGNKAED I KGTECVKSTPVTSAVQIPEV
Residue conservation: help 
Human                         PKINFV-GGNKLQSTGNKAEDIKGTECVKSTPVTSAVQIPEV

Mouse                         PKINFV-GGNKLQSTGNKTEDLKGIDCVKNTPAASAVQIPE

Rat                           PKINFVGGGNKLQSTGNKAEDLKGTDCIKNNPAASAVQIPE

Xenopus laevis                PKITFI-GGNKLQSTGNKVDDSKMSDISKATP-SSAAQTQE

Xenopus tropicalis            PKITFI-GGNKLQSTGNKVDDSKMSDSAKTTP-STAAQTQE

Zebrafish                     PKINFV-GGNKLQTTASKSDESK-ADAAKTAQSAASAPAAD
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1074 Zinc finger RNA-binding protein
Modified residue 509 – 509 N6-acetyllysine; alternate
Modified residue 516 – 516 N6-acetyllysine
Cross 509 – 509 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS ILE-461 AND THR-520;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.