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UniProtKB/Swiss-Prot Q15058: Variant p.Pro1633Ala

Kinesin-like protein KIF14
Gene: KIF14
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Variant information Variant position: help 1633
Type of variant: help LB/B
Residue change: help From Proline (P) to Alanine (A) at position 1633 (P1633A, p.Pro1633Ala).
Physico-chemical properties: help Change from medium size and hydrophobic (P) to small size and hydrophobic (A)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 1633
Protein sequence length: help 1648
Location on the sequence: help IDGSKNKGVPKRVYELHGSS P AVSSEECTPSRIQWV
Residue conservation: help 
Human                         IDGSKNKGVPKRVYELHG-SSPAVSSEECTPSRIQWV

Mouse                         ADCGKSG--PRRACEPHGDATPAVSSGDCTPNRIQW
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1648 Kinesin-like protein KIF14
Region 901 – 1648 Required for CIT-binding
Region 1600 – 1648 Disordered
Compositional bias 1633 – 1648 Polar residues



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANT ALA-1633;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.