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UniProtKB/Swiss-Prot Q2VPA4: Variant p.Ile455Val

Complement component receptor 1-like protein
Gene: CR1L
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Variant information Variant position: help 455
Type of variant: help LB/B
Residue change: help From Isoleucine (I) to Valine (V) at position 455 (I455V, p.Ile455Val).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 3
Other resources: help


Sequence information Variant position: help 455
Protein sequence length: help 569
Location on the sequence: help RINYSCTTGHRLIGHSSAEC I LSGNTAHWSMKPPICQQIFC
Residue conservation: help 
Human                         RINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC-QQIFC

Mouse                         --------------------------------------GVI

Rat                           NVALECEDGYTLEGSSQSQC---QSDASWDPPLPKCVSQVI
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 33 – 569 Complement component receptor 1-like protein
Domain 411 – 472 Sushi 7
Disulfide bond 440 – 470
Alternative sequence 444 – 444 H -> F. In isoform 2 and isoform 3.
Alternative sequence 445 – 569 Missing. In isoform 2 and isoform 3.



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2); NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-526 (ISOFORM 1); VARIANTS ASP-402 AND VAL-455;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.