Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot O14974: Variant p.Cys116Trp

Protein phosphatase 1 regulatory subunit 12A
Gene: PPP1R12A
Feedback?
Variant information Variant position: help 116
Type of variant: help LB/B
Residue change: help From Cysteine (C) to Tryptophan (W) at position 116 (C116W, p.Cys116Trp).
Physico-chemical properties: help Change from medium size and polar (C) to large size and aromatic (W)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 116
Protein sequence length: help 1030
Location on the sequence: help GANINQPDNEGWIPLHAAAS C GYLDIAEFLIGQGAHVGAVN
Residue conservation: help 
Human                         GANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN

Mouse                         GANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN

Rat                           GANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN

Chicken                       GANINQPDNEGWIPLHAAASCGYLDIAEYLISQGAHVGAVN

Zebrafish                     GACINQPDNEGWIPLHAAASCGYLDIAEYLISQGASVGVVN
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1030 Protein phosphatase 1 regulatory subunit 12A
Repeat 105 – 134 ANK 3
Modified residue 100 – 100 (3S)-3-hydroxyasparagine; by HIF1AN; partial



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.