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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot O14974: Variant p.Thr305Pro

Protein phosphatase 1 regulatory subunit 12A
Gene: PPP1R12A
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Variant information Variant position: help 305
Type of variant: help LB/B
Residue change: help From Threonine (T) to Proline (P) at position 305 (T305P, p.Thr305Pro).
Physico-chemical properties: help Change from medium size and polar (T) to medium size and hydrophobic (P)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 305
Protein sequence length: help 1030
Location on the sequence: help KKQNLLHSEKRDKKSPLIES T ANMDNNQSQKTFKNKETLII
Residue conservation: help 
Human                         KKQNLLHSEKRD-KKSPLIESTANMDNNQSQKTFKNKETLII

Mouse                         KKQTLLHSEKRD-KKSPLIESTANMENNQPQKAFKNKETLI

Rat                           KKQNLLHSEKRD-KKSPLIESTANMENNQPQKTFKNKETLI

Chicken                       KKQNLLHSEKRE-KKSPLIESTANLDNNQTQKTFKNKETLI

Zebrafish                     KKQNLLLSEKKDVKKSPLIETTTTGDNNQSVKPLKSKETLL
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1030 Protein phosphatase 1 regulatory subunit 12A
Region 290 – 628 Disordered
Compositional bias 302 – 316 Polar residues
Modified residue 299 – 299 Phosphoserine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.