Variant position: 79 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 128 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human TMTNKFTVGKESNIQTMGGK TFKATVQMEGGKLVVNFPNYH
Mouse IMSNKFTIGKECEMQTMGGK KFKATVKMEGGKVVAEFPNYH
Rat IMSNKFTIGKECEMQTMGGK KFKATVKMEGGKVVADFPNYH
Pig SITNTFTIGKECDIETIGGK KFKATVQMEGGKVVVNSPNYH
Bovine SISNNFTIGKETEMETVGNK KFKVTVKMEGGKVVVDSANYH
Rabbit IMTNKFTIGKESEIQTFGGK KFKAVVNMEGGKVVANFPNYQ
Caenorhabditis elegans NTTLSFKLGQEFDETTPDGR TVKSVVNFENGKFIHIQKKIK
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
2 – 128 Gastrotropin
Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals.
Fisher E.; Grallert H.; Klapper M.; Pfaefflin A.; Schrezenmeir J.; Illig T.; Boeing H.; Doering F.;
Mol. Genet. Metab. 98:400-405(2009)
Cited for: VARIANT MET-79;
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