Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q6NTE8: Variant p.Gln231Arg

MRN complex-interacting protein
Gene: MRNIP
Feedback?
Variant information Variant position: help 231
Type of variant: help LB/B
Residue change: help From Glutamine (Q) to Arginine (R) at position 231 (Q231R, p.Gln231Arg).
Physico-chemical properties: help Change from medium size and polar (Q) to large size and basic (R)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 231
Protein sequence length: help 343
Location on the sequence: help PGKELWSPIQQVTATSSKWA Q FVLPPRKSSHVDSEQPRSLQ
Residue conservation: help 
Human                         PGKELWSPIQQ------VTATSSKWAQFVLPPRKSSHVDSEQ-PRSLQ

Mouse                         PRWKLPSPVTQ------VNAPSSKWARFLLAPGNSPQVD-E

Bovine                        PRGEPPCPAQQ------VR-TMSKWEQCL---GNSSHLDTE

Zebrafish                     QSESPSVSSHQKFGESTIENKDSKWNKFL---TIVPTQDKE
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 343 MRN complex-interacting protein
Region 213 – 237 Necessary for the association with the MRN complex
Region 230 – 324 Disordered
Alternative sequence 230 – 343 Missing. In isoform 2.
Mutagenesis 213 – 237 Missing. Reduces the association with the MRN complex.



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1); NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3-343 (ISOFORM 3); VARIANTS GLY-154 AND ARG-231; Submission
Zhang W.; Yuan Z.; Wan T.; Cao X.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 113-343 (ISOFORM 1); VARIANT ARG-231;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.