Variant position: 227 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 602 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human QKNIAAFGGNPKSVTLFGES AGAASVSLHLLSPGSHSLFTR
Mouse QRNIAAFGGNPKSITIFGES AGAASVSLHLLCPQSYPLFTR
Bovine QKNIAAFGGNPKSVTLFGES AGAASVSLHLLSPESHPLFTR
Rabbit QKNIAAFGGNPKSVTLFGES AGAASVSLHLLSPRSHPLFTR
Cat QKNIAAFGGNPKSVTLFGES AGAGSVSLHLLSPRSQPLFTR
Horse QKNIAAFGGNPRSVTLFGES AGAASVSLHLLSPRSQPLFTR
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Identification of a point mutation associated with a silent phenotype of human serum butyrylcholinesterase - a case of familial cholinesterasemia.
Sakamoto N.; Hidaka K.; Fujisawa T.; Maeda M.; Iuchi I.;
Clin. Chim. Acta 274:159-166(1998)
Cited for: VARIANT BCHED VAL-227;
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