Type | Positions | Description |
Chain |
2 – 709 |
Caprin-1 |
Region |
524 – 709 |
Disordered |
Modified residue |
625 – 625 |
Phosphotyrosine; by EPHA4 |
Modified residue |
626 – 626 |
Omega-N-methylarginine |
Modified residue |
633 – 633 |
Omega-N-methylarginine |
Modified residue |
636 – 636 |
Phosphotyrosine; by EPHA4 |
Mutagenesis |
608 – 608 |
R -> K. Abolished ability to undergo liquid-liquid phase separation for the formation of a membraneless compartment; when associated with K-612, K-616, K-619, K-626, K-633, K-640, K-660, K-667, K-676, K-684, K-688, K-690, K-695 and K-698. |
Mutagenesis |
612 – 612 |
R -> A. Major reduction in MYC and CCND2 RNA-binding; when associated with A-633 and A-690. |
Mutagenesis |
612 – 612 |
R -> K. Abolished ability to undergo liquid-liquid phase separation for the formation of a membraneless compartment; when associated with K-608, K-616, K-619, K-626, K-633, K-640, K-660, K-667, K-676, K-684, K-688, K-690, K-695 and K-698. |
Mutagenesis |
616 – 616 |
R -> K. Abolished ability to undergo liquid-liquid phase separation for the formation of a membraneless compartment; when associated with K-608, K-612, K-619, K-626, K-633, K-640, K-660, K-667, K-676, K-684, K-688, K-690, K-695 and K-698. |
Mutagenesis |
619 – 619 |
R -> K. Abolished ability to undergo liquid-liquid phase separation for the formation of a membraneless compartment; when associated with K-608, K-612, K-616, K-626, K-633, K-640, K-660, K-667, K-676, K-684, K-688, K-690, K-695 and K-698. |
Mutagenesis |
626 – 626 |
R -> K. Abolished ability to undergo liquid-liquid phase separation for the formation of a membraneless compartment; when associated with K-608, K-612, K-616, K-619, K-633, K-640, K-660, K-667, K-676, K-684, K-688, K-690, K-695 and K-698. |
Mutagenesis |
633 – 633 |
R -> A. Major reduction in MYC and CCND2 RNA-binding; when associated with A-612 and A-690. |
Mutagenesis |
633 – 633 |
R -> K. Abolished ability to undergo liquid-liquid phase separation for the formation of a membraneless compartment; when associated with K-608, K-612, K-616, K-619, K-626, K-640, K-660, K-667, K-676, K-684, K-688, K-690, K-695 and K-698. |