Variant position: 59 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 84 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human PQDRAGARASWMPMFQ-RR-RR RDTHFPICIFCCGCCHRSKCG
Mouse PLHGEESRADIAIPMQ-KR-RK RDTNFPICIFCCKCCNNSQ
Rat PWHGAESKTDDSALLMLKR-RK RDTNFPICLFCCKCCKNSS
Pig TQDTAGATAGLTPVAQ--R-LR RDTHFPICIFCCGCCRKAI
HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype.
Jacolot S.; Le Gac G.; Scotet V.; Quere I.; Mura C.; Ferec C.;
Cited for: VARIANTS HFE2B GLY-59 AND ASP-71;
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