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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q5D862: Variant p.Tyr881Ser

Filaggrin-2
Gene: FLG2
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Variant information Variant position: help 881
Type of variant: help LB/B
Residue change: help From Tyrosine (Y) to Serine (S) at position 881 (Y881S, p.Tyr881Ser).
Physico-chemical properties: help Change from large size and aromatic (Y) to small size and polar (S)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 881
Protein sequence length: help 2391
Location on the sequence: help HGSSSGQTSGFGQHRSSSGQ Y SGFGQHGSGSGQSSGFGQHG
Residue conservation: help 
Human                         HGSSSGQTSGFGQHRSSSG-QYSGFGQHGSGSGQSSGFGQHG

Mouse                         QEAGHGQSSSSWQHGTGAGNQSSGYGEHKSGPSHSSRSWHH
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 2391 Filaggrin-2
Region 406 – 2391 Disordered



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.