Variant position: 33 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 716 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human ERLKLLQEEEERRLKEEEEA RLKYEKEEMERLEIQRIEKEK
Mouse ERLRLMQEEEERRLKEEEEA RLKFEKEEQERLEIQRIEREK
Bovine DRLKQILEEEEKRQKEEEEA RVKYEKEEMERLEIQRIENEK
Zebrafish EKERLQREEEEKRQREAEEA RLIAEREENERLERERIEQEK
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 716 Dynein intermediate chain CFAP94, axonemal
20 – 88 Glu-rich
1 – 60 MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAK -> M. In isoform 4.
1 – 40 Missing. In isoform 2.
A V141L polymorphism of the human LRMP gene is associated with survival of lung cancer patients.
Manenti G.; Galbiati F.; Pettinicchio A.; Spinola M.; Piconese S.; Leoni V.P.; Conti B.; Ravagnani F.; Incarbone M.; Pastorino U.; Dragani T.A.;
Cited for: VARIANT SER-33;
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