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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q99650: Variant p.Pro959Arg

Oncostatin-M-specific receptor subunit beta
Gene: OSMR
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Variant information Variant position: help 959
Type of variant: help LB/B
Residue change: help From Proline (P) to Arginine (R) at position 959 (P959R, p.Pro959Arg).
Physico-chemical properties: help Change from medium size and hydrophobic (P) to large size and basic (R)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 959
Protein sequence length: help 979
Location on the sequence: help APHCSEYKMQMAVSLRLALP P PTENSSLSSITLLDPGEHYC
Residue conservation: help 
Human                         APHCSEYKMQMAVSLRLALPPPTENSSLSSITLLDPGEHYC

Mouse                         PVHGSEYKRQMVVPGSLASPSLKEDNSLTSTVLLGQGEQ--

Rat                           PVHGSEYKKQMALPGSLTSASLKENN-LTS-----------
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 28 – 979 Oncostatin-M-specific receptor subunit beta
Topological domain 762 – 979 Cytoplasmic
Alternative sequence 343 – 979 Missing. In isoform 2.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.