Variant position: 149 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 347 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human L---------DSPNAVHE-VEKWLPRLHAL VVGPGLGRDDALLRNVQGILE
Rhesus macaque L---------DSPSAVDE-VEKWLPRLHAL VFHCERGTQPG
Mouse L---------DSSNAVEE-VEKWLPRLHAL VVGPGLGRDDL
Rat L---------DSSDAVEE-VEKWLPRLHAL VVGPGLGRDDL
Bovine L---------DSPEAVRD-VEQWLPRLHAL VVGPGLGRDDA
Zebrafish L---------DSPNAVEE-IEKWLPRLHSV VVGPGLGREDM
Caenorhabditis elegans M---------TANS-----IIPKLSRMDAI VIGPGLGRNPN
Drosophila L---------DCVDAVER-IAPWLERLHVV VIGPGLGREPG
Slime mold ----------EKNDPSD--IIPWLLSLHVI VVGPGLGRSSG
Baker's yeast LRMSNTKLDVDMDEQRKK-INSLLDRIHVV VIGPGLGRDPL
Fission yeast LREKDKAGPEDSVDKCFELIKPMMGRLHAI VIGPGLGRDEW
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 347 ATP-dependent (S)-NAD(P)H-hydrate dehydratase
53 – 344 YjeF C-terminal
153 – 153 NADPHX; via amide nitrogen
1 – 221 Missing. In isoform 3.
No reference for the current variant in UniProtKB/Swiss-Prot.
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