Variant position: 152 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 347 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human PNAVHE-VEKWLPRLHALVVG PGLGRDDALLRNVQGILEVSK
Rhesus macaque PSAVDE-VEKWLPRLHALVFH CERGTQPGFL-FWQGILEAS
Mouse SNAVEE-VEKWLPRLHALVVG PGLGRDDLLLNNVRGILEST
Rat SDAVEE-VEKWLPRLHALVVG PGLGRDDLLLNNVRGILEST
Bovine PEAVRD-VEQWLPRLHALVVG PGLGRDDALLENVKGILEAS
Zebrafish PNAVEE-IEKWLPRLHSVVVG PGLGREDMLLKNAKEIIERS
Caenorhabditis elegans NS-----IIPKLSRMDAIVIG PGLGRNPNIWPLMQELFEFV
Drosophila VDAVER-IAPWLERLHVVVIG PGLGREPGILKTASNVLKLC
Slime mold NDPSD--IIPWLLSLHVIVVG PGLGRSSGAWSCASEVIKAA
Baker's yeast DEQRKK-INSLLDRIHVVVIG PGLGRDPLMLKSIKDIIRYI
Fission yeast VDKCFELIKPMMGRLHAIVIG PGLGRDEWMQEIMAKVIEYA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 347 ATP-dependent (S)-NAD(P)H-hydrate dehydratase
53 – 344 YjeF C-terminal
153 – 153 NADPHX; via amide nitrogen
1 – 221 Missing. In isoform 3.
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.