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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q86Y33: Variant p.Arg503Trp

Cell division cycle protein 20 homolog B
Gene: CDC20B
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Variant information Variant position: help 503
Type of variant: help LB/B
Residue change: help From Arginine (R) to Tryptophan (W) at position 503 (R503W, p.Arg503Trp).
Physico-chemical properties: help Change from large size and basic (R) to large size and aromatic (W)
BLOSUM score: help -3
Other resources: help


Sequence information Variant position: help 503
Protein sequence length: help 519
Location on the sequence: help GGFFGHRGRVLHLSLSPDQT R VFSAAADGTASVWNCY
Residue conservation: help 
Human                         GGFFGHRGRVLHLSLSPDQTRVFSAAADGTASVWNCY-

Mouse                         GGFFGHRDRVLHLSLSPDQTRLFSAAADGTACVWKCC

Xenopus laevis                NDYYGHKGRVLHLALSPDQRRIFSAAANGTANIWKYG
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 519 Cell division cycle protein 20 homolog B
Repeat 487 – 519 WD 7
Alternative sequence 214 – 519 Missing. In isoform 5.
Alternative sequence 373 – 519 Missing. In isoform 4.



Literature citations
CDC20-like protein.
Hayashi A.; Saito T.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4); VARIANTS CYS-121; ALA-496 AND TRP-503; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 5); VARIANTS CYS-121; ALA-496 AND TRP-503;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.