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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q6PJF5: Variant p.Asp528Tyr

Inactive rhomboid protein 2
Gene: RHBDF2
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Variant information Variant position: help 528
Type of variant: help LB/B
Residue change: help From Aspartate (D) to Tyrosine (Y) at position 528 (D528Y, p.Asp528Tyr).
Physico-chemical properties: help Change from medium size and acidic (D) to large size and aromatic (Y)
BLOSUM score: help -3
Other resources: help


Sequence information Variant position: help 528
Protein sequence length: help 856
Location on the sequence: help CIQTQRKDCSETLATFVKWQ D DTGPPMDKSDLGQKRTSGAV
Residue conservation: help 
Human                         CIQTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAV

                              CIQTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAV

Mouse                         CIQTLKKDCSETLATFVKWQNDTGPS-DKSDLSQKQPSAVV

Xenopus tropicalis            CVQTHRKDCSETLATFIKWPEHDAPVLDEVT-GMKRTSGAV
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 856 Inactive rhomboid protein 2
Topological domain 431 – 660 Lumenal
Turn 528 – 530



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.