Variant position: 244 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 393 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human EVGSDCTTIHYNYMCNSSCM GGMNRRPILTIITLEDSSGNL
Rhesus macaque EVGSDCTTIHYNYMCNSSCM GGMNRRPILTIITLEDSSGNL
Mouse EAGSEYTTIHYKYMCNSSCM GGMNRRPILTIITLEDSSGNL
Rat EVGSDYTTIHYKYMCNSSCM GGMNRRPILTIITLEDSSGNL
Pig EVGSDCTTIHYNFMCNSSCM GGMNRRPILTIITLEDASGNL
Bovine EIDSECTTIHYNFMCNSSCM GGMNRRPILTIITLEDSCGNL
Rabbit EVGSDCTTIHYNYMCNSSCM GGMNRRPILTIITLEDSSGNL
Sheep EIESECTTIHYNFMCNSSCM GGMNRRPILTIITLEDSRGNL
Cat EVGSDCTTIHYNFMCNSSCM GGMNRRPIITIITLEDSNGKL
Chicken EVGSDCTTVLYNFMCNSSCM GGMNRRPILTILTLEGPGGQL
Xenopus laevis QVGTECTTVLYNYMCNSSCM GGMNRRPILTIITLETPQGLL
Zebrafish QLGAEWTTVLLNYMCNSSCM GGMNRRPILTIITLETQEGQL
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.