Variant position: 319 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 446 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human CMLTTATAHDGDVNVISWSR REPFLL-SGGDDGALKIWDLRQ
Mouse CMLTTATAHDGDVNVISWSR REPFLL-SGGDDGALKVWDLR
Rat CMLTTAAAHDGDVNVISWSR REPFLL-SGGDDGTLKVWDLR
Bovine CMLTTATAHDGDVNVINWSH REPFLL-SGGDDGALKVWDLR
Slime mold ITVKA---HTADVNVISWSR NVEYLLVSGCDDGSFRVWDLR
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 446 Glutamate-rich WD repeat-containing protein 1
298 – 343 WD 5
Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.
Nagase T.; Kikuno R.; Ohara O.;
DNA Res. 8:319-327(2001)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-446; VARIANT GLN-319;
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