Variant position: 663 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 886 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VCLLLAKTLFLAGIHKTDNK MGCAIIAGFLHYLFLACFFWM
Mouse VCLFLAKILFLTGIDKTDNQ TACAIIAGFLHYLFLACFFWM
Rat VCLFLAKILFLTGIDKTDNQ TACAIIAGFLHYLFLACFFWM
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
21 – 886 Adhesion G protein-coupled receptor E1
657 – 666 Extracellular
599 – 663 Missing. In isoform 2.
EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments.
Baud V.; Chissoe S.L.; Viegas-Pequignot E.; Diriong S.; N'Guyen V.C.; Roe B.A.; Lipinski M.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1); VARIANTS THR-57; ARG-140; ASN-174; SER-254; VAL-298; MET-389; VAL-424; GLN-496; VAL-539 AND THR-663;
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