Variant position: 246 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 902 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human TPEDPWSLYGPSPGGRGPED SWLLLSAPGPTPASPRPASPC
Mouse TPEDPWSLYGPSSGGRAPED SWLLLSAPGPVPASPRPASPC
Rat TPEDPWSLYGPSSGGRAPED SWLLLSAPGPIPASPRPASPC
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 902 Nuclear factor of activated T-cells, cytoplasmic 4
208 – 369 Disordered
213 – 293 2 approximate SP repeats
1 – 712 Missing. In isoform 22, isoform 23 and isoform 24.
1 – 465 Missing. In isoform 19, isoform 20 and isoform 21.
No reference for the current variant in UniProtKB/Swiss-Prot.
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