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UniProtKB/Swiss-Prot O60494: Variant p.Pro1971Thr

Cubilin
Gene: CUBN
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Variant information Variant position: help 1971
Type of variant: help LB/B
Residue change: help From Proline (P) to Threonine (T) at position 1971 (P1971T, p.Pro1971Thr).
Physico-chemical properties: help Change from medium size and hydrophobic (P) to medium size and polar (T)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 1971
Protein sequence length: help 3623
Location on the sequence: help ISGKGFLLEWFAVDAPDGVL P TIAPGACGGFLRTGDAPVFL
Residue conservation: help 
Human                         ISGKG-FLLEWFAVDAPDGVLPTIAPG---ACGGFLRTGDAPVF-L

                              ITGKG-FLLEWFAVNASGGPLPTIATG---ACGGFLRTGDA

Mouse                         KSGRG-FLLEWFAVDVSNVTLPTIAPG---ACGGYMVTGDT

Rat                           VSGRG-FLLEWFAVDVSDSTPPTIAPG---ACGGFMVTGDT

Pig                           ISGRG-FLLEWFAMDASDGPLPTIATG---ACGGFLRTGDA

Caenorhabditis elegans        KSDKFSFTWDPVPLNYRNLTLAKDKPAKVYDCGGDLTPTYE

Drosophila                    TSNRGPFKLNWNRLSKEALRSNRTAEERTRQCGNQLITIDR
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 36 – 3623 Cubilin



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.