Variant position: 4331 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 4391 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GEELVSGRSPGPNVAVNAKG SVYIGGAPDVATLTGGRFSSG
Mouse GEDLVTGRSPGPNVAVNTKD IIYIGGAPDVATLTRGKFSSG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
22 – 4391 Basement membrane-specific heparan sulfate proteoglycan core protein
3687 – 4391 Endorepellin
4197 – 4391 LG3 peptide
4201 – 4389 Laminin G-like 3
4325 – 4325 Calcium; via carbonyl oxygen
4327 – 4327 Calcium
4327 – 4327 N -> A. Retains proper folding. Reduced calcium ion binding.
No reference for the current variant in UniProtKB/Swiss-Prot.
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