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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q13087: Variant p.Pro382Ala

Protein disulfide-isomerase A2
Gene: PDIA2
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Variant information Variant position: help 382
Type of variant: help LB/B
Residue change: help From Proline (P) to Alanine (A) at position 382 (P382A, p.Pro382Ala).
Physico-chemical properties: help Change from medium size and hydrophobic (P) to small size and hydrophobic (A)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 382
Protein sequence length: help 525
Location on the sequence: help AFCHAVLNGQVKPYLLSQEI P PDWDQRPVKTLVGKNFEQVA
Residue conservation: help 
Human                         AFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVA

Mouse                         AFCQAVLHGEIKHYLLSQEIPPDWDQGPVKTLVSKNFEQVA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 22 – 525 Protein disulfide-isomerase A2
Domain 367 – 496 Thioredoxin 2
Mutagenesis 364 – 364 C -> A. No effect on interchain disulfide bridge formation.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.