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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P04003: Variant p.Ala60Val

C4b-binding protein alpha chain
Gene: C4BPA
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Variant information Variant position: help 60
Type of variant: help LB/B
Residue change: help From Alanine (A) to Valine (V) at position 60 (A60V, p.Ala60Val).
Physico-chemical properties: help Change from small size and hydrophobic (A) to medium size and hydrophobic (V)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 60
Protein sequence length: help 597
Location on the sequence: help AALLPAVLGNCGPPPTLSFA A PMDITLTETRFKTGTTLKYT
Residue conservation: help 
Human                         AALLPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYT

Mouse                         AALWVAVFGKCGPPPAIPNALPAS-DVNRTDFESHTTLKYE

Rat                           AALWVAVFGKCGPPPDLPYALPAS-EMNQTDFESHTTLRYN

Bovine                        ATLLATVLGSCGIPPYLDFAFPIN-ELNETRFETGTTLRYT
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 49 – 597 C4b-binding protein alpha chain
Domain 49 – 110 Sushi 1
Disulfide bond 50 – 96
Beta strand 57 – 63



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.