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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P04066: Variant p.Arg2Trp

Tissue alpha-L-fucosidase
Gene: FUCA1
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Variant information Variant position: help 2
Type of variant: help LB/B
Residue change: help From Arginine (R) to Tryptophan (W) at position 2 (R2W, p.Arg2Trp).
Physico-chemical properties: help Change from large size and basic (R) to large size and aromatic (W)
BLOSUM score: help -3
Polymorphism: help There are two common alleles of FUCA1; FUCA1*1; also known as Fu1; has Arg-281 and FUCA1*2; also known as Fu2; has Gln-281.
Other resources: help


Sequence information Variant position: help 2
Protein sequence length: help 466
Location on the sequence: help M R APGMRSRPAGPALLLLLLFL
Residue conservation: help 
Human                         MRAPGMRSRPAGPALLLLLL---FL

                              MKPWAVGLGPPPPAVPLLLL--

Mouse                         --------------MLLLLL--

Rat                           --MWDLKSEWWAVGFGLLLL--

Bovine                        MRSWVVGARLLLLLQLVLVLGA

Caenorhabditis elegans        ---------MIFLIFSILFL--

Drosophila                    ----MAISAWMPLLVALIVV--

Slime mold                    -------MKMIIIFFILLIL--
Sequence annotation in neighborhood: help
TypePositionsDescription
Signal peptide 1 – 31



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.