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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9BZP6: Variant p.Phe377Leu

Acidic mammalian chitinase
Gene: CHIA
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Variant information Variant position: help 377
Type of variant: help LB/B
Residue change: help From Phenylalanine (F) to Leucine (L) at position 377 (F377L, p.Phe377Leu).
Physico-chemical properties: help Change from large size and aromatic (F) to medium size and hydrophobic (L)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 377
Protein sequence length: help 476
Location on the sequence: help AMVWAIDLDDFTGTFCNQGK F PLISTLKKALGLQSASCTAP
Residue conservation: help 
Human                         AMVWAIDLDDFTGTFCNQGKFPLISTLKKALGLQSASCTAP

Mouse                         AMIWAIDLDDFTGSFCDQGKFPLTSTLNKALGISTEGCTAP

Rat                           AMIWAIDLDDFTGSFCDQGKFPLTSTLNKALDIPTAGCTAP

Bovine                        AMVWAIDLDDFTGTFCNQGKFPLINTLKDALGLKSATCNAS
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 22 – 476 Acidic mammalian chitinase
Domain 22 – 390 GH18
Binding site 360 – 360
Disulfide bond 49 – 394



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.