Variant position: 240 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 664 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human FALDLLMENGECRGVIALCI EDGSIHRIRAKNTVVATGGYG
Mouse FALDLLMENGECRGVIALCI EDGSIHRIRAKNTVIATGGYG
Rat FALDLLMENGECRGVIALCI EDGSIHRIRAKNTIIATGGYG
Pig FALDLLMENGECRGVIALCI EDGSIHRIRARNTVVATGGYG
Bovine FALDLLMESGECRGVIALCI EDGSIHRIRARNTVIATGGYG
Chicken FALDLLMENGECRGVIALCI EDGTIHRFRAKNTVIATGGYG
Xenopus tropicalis FALDLLMENGECRGVIALCM EDGSIHRFRAKNTVIATGGYG
Zebrafish FALDLLMEDGECKGVIALCM EDGSIHRFRAKNTVIATGGYG
Caenorhabditis elegans FALDLIMENGVCVGVIAMDL EDGTIHRFRSKNTVLATGGYG
Drosophila FALDLIFEDGECRGVLALNL EDGTLHRFRAKNTVIATGGYG
Slime mold FVTDLIMENGDCRGVVAINL EDGTIHRFRSHATVIATGGYG
Baker's yeast FALDLLTHNGEVVGVIAYNQ EDGTIHRFRAHKTIIATGGYG
Fission yeast FAMDLIMEGGECRGVIAMNL EDGSIHRFRAHKTILATGGYG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
43 – 664 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
250 – 250 N6-acetyllysine; alternate
250 – 250 N6-succinyllysine; alternate
126 – 270 Missing. In isoform 3.
239 – 241
No reference for the current variant in UniProtKB/Swiss-Prot.
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