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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P05162: Variant p.Val119Ile

Galectin-2
Gene: LGALS2
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Variant information Variant position: help 119
Type of variant: help LB/B
Residue change: help From Valine (V) to Isoleucine (I) at position 119 (V119I, p.Val119Ile).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 3
Other resources: help


Sequence information Variant position: help 119
Protein sequence length: help 132
Location on the sequence: help DGHELTFPNRLGHSHLSYLS V RGGFNMSSFKLKE
Residue conservation: help 
Human                         DGHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE

Mouse                         DGHQLTFPNRLGHNQLHYLSM-GGLQISSFKLE-

Rat                           DGHSLTFPNRLGHNHLRYLSM-DGLQISSFKLE-
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 132 Galectin-2
Domain 4 – 131 Galectin
Beta strand 116 – 131



Literature citations
Evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes.
Gitt M.A.; Barondes S.H.;
Proc. Natl. Acad. Sci. U.S.A. 83:7603-7607(1986)
Cited for: PRELIMINARY NUCLEOTIDE SEQUENCE [MRNA] OF 6-132; VARIANT ILE-119;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.