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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P17931: Variant p.Arg183Lys

Galectin-3
Gene: LGALS3
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Variant information Variant position: help 183
Type of variant: help LB/B
Residue change: help From Arginine (R) to Lysine (K) at position 183 (R183K, p.Arg183Lys).
Physico-chemical properties: help Similar physico-chemical property. Both residues are large size and basic.
BLOSUM score: help 2
Other resources: help


Sequence information Variant position: help 183
Protein sequence length: help 250
Location on the sequence: help FNENNRRVIVCNTKLDNNWG R EERQSVFPFESGKPFKIQVL
Residue conservation: help 
Human                         FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVL

                              FNEDNKRVIVCNTKLDNIWGKEERQAAFPFESGKPFKIQVL

Mouse                         FNENNRRVIVCNTKQDNNWGKEERQSAFPFESGKPFKIQVL

Rat                           FNENNRRVIVCNTKQDNNWGREERQSAFPFESGKPFKIQVL

Rabbit                        FNENNRRVIVCNTKVDNNWGREERQTTFPFEIGKPFKIQVL
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 2 – 250 Galectin-3
Domain 118 – 248 Galectin
Binding site 181 – 187
Modified residue 188 – 188 Phosphoserine
Disulfide bond 173 – 173 Interchain



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.