Variant position: 815 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 1621 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human IARPLENENQEFLKSLKEES VEAVKSLETEILESLKSAGQE
Mouse VVRSLDKENQESLVSLNEGG METVKSSETENIESLETVG-E
Rat IARSLGKENQESLVSLKEKG IETVKSLETEIIEPLETAE-E
Zebrafish ------DEHNLPQIELNEDQ SEAEEENQKE----------K
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 1621 Nestin
314 – 1621 Tail
820 – 820 Phosphoserine
831 – 831 Phosphoserine
811 – 811 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate
811 – 811 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate
Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma.
Ohira M.; Morohashi A.; Nakamura Y.; Isogai E.; Furuya K.; Hamano S.; Machida T.; Aoyama M.; Fukumura M.; Miyazaki K.; Suzuki Y.; Sugano S.; Hirato J.; Nakagawara A.;
Cancer Lett. 197:63-68(2003)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 604-1621; VARIANT ILE-815;
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