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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9NQS3: Variant p.Arg432Leu

Nectin-3
Gene: NECTIN3
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Variant information Variant position: help 432
Type of variant: help LB/B
Residue change: help From Arginine (R) to Leucine (L) at position 432 (R432L, p.Arg432Leu).
Physico-chemical properties: help Change from large size and basic (R) to medium size and hydrophobic (L)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 432
Protein sequence length: help 549
Location on the sequence: help GALFIVLVSVLAGIFCYRRR R TFRGDYFAKNYIPPSDMQKE
Residue conservation: help 
Human                         GALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKE

Mouse                         GALFLVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKE

Zebrafish                     GALFLLLLLILAGVYYQRQRRTFRGDYYTKQYHGPSDMQKA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 58 – 549 Nectin-3
Topological domain 426 – 549 Cytoplasmic
Alternative sequence 357 – 549 DPPTTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNNVENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHVDGSVISRREWYV -> DVPFKQTSSIAVAGAVIGAVLALFIIAIFVTVLLTPRKKRPSYLDKVIDLPPTHKPPPLYEERSPPLPQKDLFQPEHLPLQTQFKEREVGNLQHSNGLNSRSFDYEDENPVGEDGIQQMYPLYNQMCYQDRSPGKHHQNNDPKRVYIDPREHYV. In isoform 3.
Alternative sequence 367 – 549 Missing. In isoform 2.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.